|Title||Evidence for Host-Genotype Associations of Borrelia burgdorferi Sensu Stricto|
|Publication Type||Journal Article|
|Year of Publication||2016|
|Authors||Mechai S, Margos G, Feil EJ, Barairo N, Lindsay LR, Michel P, Ogden NH|
Different genotypes of the agent of Lyme disease in North America, Borrelia burgdorferi sensu stricto, show varying degrees of pathogenicity in humans.Correspondence analysis and generalized linear mixed effect models revealed significant associations between B. burgdorferi genotypes and host species (in particular chipmunks, and white-footed mice and deer mice), supporting the hypotheses that host adaptation contributes to the phylogenetic structure and possibly the observed variation in pathogenicity in humans.