|Title||Construction and characterization of a Borrelia burgdorferi strain with conditional expression of the essential telomere resolvase, ResT.|
|Publication Type||Journal Article|
|Year of Publication||2014|
|Authors||Bandy NJ, Salman-Dilgimen A, Chaconas G|
Borrelia species are unique in the bacterial world in possessing segmented genomes which sometimes contain over 20 genetic elements. Most elements are linear and contain covalently closed hairpin ends requiring a specialized process, telomere resolution, for their generation. Treatment of DNA from the ResT-depleted strain with ResT in vitro revealed the presence of replicated telomeres expected in replication intermediates.